For many couples, the path to parenthood winds through unexpected twists and turns. When natural conception seems elusive, the medical world extends a beacon of hope in the form of In Vitro Fertilisation (IVF).

This revolutionary procedure has been the answer to countless prayers, bridging the gap between infertility struggles and the joy of parenthood.

However, like any medical intervention, IVF doesn’t guarantee uniform success for everyone. Why do some IVF procedures succeed while others might not? What can one do to tilt the odds in their favour?

In this blog, we’ll unravel the intricate factors and strategies that can significantly bolster the success rate of IVF treatments.

Boosting IVF Success Rate

There are numerous factors that contribute to the success of an IVF procedure. So it’s critical to check all the boxes for improving the chances of success. Here are some most important factors that a patient must know about:

• Self and Doctor Confidence: Faith is a potent healer. Trusting oneself and having unwavering confidence in your chosen physician is fundamental. This trust ensures that you adhere to guidelines and medical advice, thereby increasing the likelihood of a positive outcome.
• Choosing the Right IVF Center: Not all IVF centres are created equal. Research and select a centre known for its expertise, advanced equipment, and compassionate care. Accreditation, success stories, and the experience of the medical staff can provide valuable insights. Read More: How to choose right IVF center?
• Understanding the Global Success Rate of IVF: IVF’s success isn’t guaranteed in the initial cycle. On average, globally, the first IVF cycle has a 40% success rate. But don’t be disheartened. As issues get identified and addressed, the potential for success in subsequent cycles, such as the second one, increases, often reaching up to 60%.
  
  Read More: Understanding IVF Success Rate

Now, let’s take a look at some methods that can enhance the IVF success rate in certain cases.

The Role of Ovarian Rejuvenation in Enhancing IVF Success

One method that has gained traction in enhancing the success rate of IVF is ‘ovarian rejuvenation’. It aims to improve the quality of the eggs, which is vital for successful conception.

Ovarian Rejuvenation Techniques:

• PRP (Platelet-Rich Plasma) Treatment: Here, a concentration of one’s platelets is introduced into the ovaries. This concentration contains growth factors that can stimulate the ovaries, potentially improving egg quality.
• ACRS (Autologous Cell Rejuvenation Serum) and Stem Cell Therapy: Stem cells have the unique ability to develop into many different cell types. By introducing them into the ovaries, there’s a potential for improved egg health and vitality.

What Exactly is Ovarian Rejuvenation?:

The process involves introducing specific factors, such as PRP or stem cells, into the ovaries. The aim is to enhance the health and vitality of eggs.

After undergoing this procedure, it’s typically recommended to pause fertility treatments for about a month to six weeks to allow the body to recover and respond.

Improving Uterine Receptivity

A crucial aspect of IVF’s success is the ability of the embryo to attach itself to the uterus. If this doesn’t occur, even the healthiest of embryos won’t result in a pregnancy.

Employing Embryo Glue: This substance enhances the embryo’s ability to stick to the uterus, thereby potentially increasing the chances of a successful pregnancy.

Endometrial Rejuvenation

Endometrial rejuvenation refers to the series of treatments aimed at improving the quality and thickness of the endometrial lining of the uterus. These procedures enhance the receptivity of the endometrium,

optimising it for successful implantation of an embryo. By promoting a healthier environment in the uterus, endometrial rejuvenation increases the chances of pregnancy during fertility treatments.

• Endometrial PRP: Similar to ovarian PRP, this involves introducing platelet-rich plasma into the endometrial lining to improve its thickness and health.
• Subendometrial Injections of Stem Cells: Stem cells, given their potential to rejuvenate, are introduced to the region beneath the endometrial lining to enhance its quality.
• Adhesiolysis: This procedure addresses potential adhesions or scar tissue in the uterus that might be hindering successful implantation.

Addressing the Third IVF Cycle

While many might achieve success in the initial cycles of IVF, for some, the journey extends further. In fact, some couples might need up to 3 cycles for a successful pregnancy. During the third cycle, a more comprehensive examination is often undertaken.

Immunological Tests: These tests evaluate if there’s an immune response hindering the embryo’s implantation. Such reactions can be the body’s way of inadvertently defending itself, viewing the embryo as a foreign entity.

Wrapping Up

Every individual’s IVF journey is unique, filled with its own challenges and moments of hope. By understanding the factors that play into the success rate of IVF and by working collaboratively with trusted medical professionals, the dream of parenthood becomes a tangible reality for many.

Always remember, each step, each cycle, and each procedure is a stride towards the ultimate goal: the gift of life.

In case you need any further information on the matter, our experts are here to help. Get in touch and we will answer all your questions!

• 

• About Author

  Dr. Supriya Puranik

  Gynaecologist & IVF Specialist

Dr. Supriya Puranik, a renowned gynaecologist and infertility expert, leads the IVF & Gynaecology department at Sahyadri Hospitals Momstory in Shivaji Nagar, Pune. She is committed to helping couples overcome infertility challenges.