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What is IMSI?

IMSI-IVF stands for Intracytoplasmic Morphology-Selected Sperm Injection in vitro fertilisation. It is an advanced form of intracytoplasmic sperm injection (ICSI), which involves injecting a single sperm cell into an egg to facilitate fertilisation. However, unlike ICSI, IMSI-IVF utilises high-magnification microscopy to select the best-quality sperm cell for injection.

IMSI-IVF is typically recommended for couples with severe male infertility issues, including poor sperm motility or abnormal sperm morphology. High-magnification microscopy helps identify the best-quality sperm cells with the highest chance of successfully fertilising the egg.

How does IMSI Work?

The IMSI-IVF process involves several steps, including:

  • Sperm Collection

Sperm cells are collected from the male partner or a sperm donor. The sperm samples are then analysed to determine sperm quality and quantity.

  • Sperm Selection

High-magnification microscopy is used to identify the best-quality sperm cells with the highest chance of successfully fertilising the egg.

  • Egg Retrieval

After ovarian stimulation, which involves using medication to stimulate the ovaries, mature eggs are retrieved from the woman’s ovaries using a needle under ultrasound guidance.

  • IMSI

Using a thin pipette, the selected sperm cell is injected directly into the egg. This process increases the chances of successful fertilisation and embryo development.

Who is IMSI Suitable for?

IMSI-IVF is typically recommended for couples facing severe male infertility issues, such as:

  • Low sperm count or reduced sperm motility


  • Abnormal sperm morphology


  • History of failed IVF cycles


  • Unexplained infertility that hasn’t been successfully treated using traditional IVF

IMSI-IVF is also a suitable treatment option for couples who have undergone IVF cycles before and experienced fertilisation failure. Dr. Supriya Puranik, a highly experienced IVF specialist in Pune, India, will assess your medical history and thoroughly evaluate it before recommending IMSI-IVF. During your consultation, she will discuss your options, provide counselling and support, and help you make the best decision for your family’s future.

ICSI vs IMSI - A Comprehensive Guide

ICSI and IMSI techniques have revolutionized fertility treatments, offering hope to couples and individuals striving to build families. In this comprehensive guide, we delve into the nuances of ICSI and IMSI, examining their processes, benefits, and considerations.

Benefits of IMSI

IMSI offers several benefits, including:

  • Increased chances of a successful pregnancy: IMSI increases the chances of successful fertilisation and embryo development in cases where traditional IVF might not result in pregnancy.

  • Improved sperm selection: The use of high-magnification microscopy increases the chances of selecting healthy and viable sperm cells, increasing the success rate of the procedure.

  • Reduced risk of genetic abnormalities: IMSI-IVF reduces the risk of genetic abnormalities in the embryo, increasing the chances of a healthy pregnancy.
Get in Touch:

Dr. Supriya Puranik, a leading IVF specialist in Pune, India, provides comprehensive fertility care, including IMSI-IVF. She has helped countless couples achieve their dream of parenthood and is committed to providing personalised fertility treatment plans that meet each patient’s needs. If you’re facing infertility issues, schedule a consultation with Dr. Puranik to explore the benefits of IMSI-IVF and other fertility treatment options today.

About Doctor


Dr. Supriya Puranik

Gynaecologist & IVF Specialist

Often known as the last glimmer of hope for people who have lost all hope for conceiving a child, Dr. Supriya Puranik is a leading gynaecologist, high-risk obstetrician and Head of IVF & Gynaecology department at Ankura Hospital, Pune

Patient Reviews

Patient Reviews & Feedback

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  • Om Kadel

She is excellent. And as a goddess for my family. After long time I m blessed with twins baby due to her efforts only. She used to boost me with lots of positive thoughts whenever I lost the hope. You are too supportive mam. Thanks a lot.

Even the hospital staff, Nurses, mousis,house keeping staffs are at your step when ever needed when I was admitted.

The food provided is well planned according to the diet of patients by mam. Thank you very much mam for this turn over in my life after 12 years of marriage.

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  • Ashwini Sonawane

Dr. Supriya Puranik’s mam is very sweet person I have ever met. She is very caring, her ever smiling face always gives you positive wives. Staff is also very helpful and care taking during delivery, the best hospitality service I would say…
Thank you so much Dr Puranik Mam and Team. keep up the good work


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