How to Make IVF Successful the First Time?

If you’re considering IVF (in vitro fertilisation), it’s likely you’ve already faced challenges on your fertility journey, and you want to make this opportunity count.
The decision to pursue IVF is a big one—physically, emotionally, and financially.
Naturally, one of the most pressing questions you may have is, “How can I make IVF successful the first time?”
The good news? There are practical steps you can take to maximise your chances of success right from the start.
Below, we’ll walk you through every stage of the IVF process—from preparation to aftercare—providing you with actionable advice so that you’re fully informed and confident in your approach.
What Can You Do to Boost Your IVF Success?
1. Prepare Your Body Before Treatment
IVF is not just a one-time procedure but a process that begins well before the first injection. Preparing your body is key to maximising your chances of success.
Focus on a Healthy Diet
Your nutrient intake plays a crucial role in reproductive health. Fill your plate with:
- Leafy greens, which are high in folate.
- Healthy fats, like those in avocados and nuts, which support hormone production.
- Lean proteins, such as chicken, fish, and legumes, to maintain overall health.
Avoid excessive caffeine, alcohol, and processed foods. Keep things simple with small changes, like swapping sugary snacks for fresh fruit or adding a handful of spinach to your meals.
Maintain a Healthy Weight
Being either over- or underweight can affect your hormone balance and, subsequently, your chances of a successful IVF cycle. Aim for a BMI (body mass index) between 19 and 24 for the best results.
A study published in the journal Human Reproduction found a significant correlation between obesity and lower IVF success rates. If you’re unsure about your BMI, consult your doctor—they can guide you on healthy weight management strategies.
Start a Light Exercise Routine
Moderate, consistent physical activity can improve blood circulation to your reproductive organs and reduce stress. Try incorporating yoga, walking, or gentle swimming into your weekly routine. Avoid high-intensity workouts, though, as they can interfere with ovulation and implantation.
2. Prioritise Your Emotional Health
Your mindset and emotional well-being can directly impact your body. IVF can sometimes feel like a rollercoaster, so building emotional resilience is just as important as physical preparation.
Manage Stress Levels
Chronic stress can disrupt hormone levels, which are crucial during IVF. Incorporate relaxation techniques into your day, such as mindfulness meditation, deep breathing exercises, or even a soothing activity like painting or gardening.
Seek Support
Don’t underestimate the power of connection. Whether it’s through a trusted friend, a partner, or a support group, sharing your feelings can lighten the emotional load. Some fertility clinics even offer counselling tailored to individuals or couples undergoing IVF.
3. Choose the Right Clinic and Specialist
Choosing a reputable fertility clinic and a trusted specialist can significantly impact the outcome of your IVF cycle. But how do you select the right one? Here are a few tips:
- Look for clinics with high success rates for your age group and specific circumstances. Ensure these are calculated based on live birth rates, not just pregnancies.
- Verify that the clinic uses advanced technology, such as time-lapse embryo monitoring.
- Prioritise communication—clinics that make you feel heard and supported will provide a better overall experience.
4. Follow the Stimulation Plan to the Letter
Once your IVF cycle begins, you’ll be prescribed medications to stimulate your ovaries and produce multiple eggs. These medications are carefully timed, so it’s crucial to follow your doctor’s instructions precisely.
- Use reminders (alarms, phone apps, sticky notes) to adhere to a strict schedule for taking your medications, as missing doses can affect egg quality.
- Attend all monitoring appointments to ensure your ovaries are responding well to stimulation.
5. Focus on Quality Over Quantity During Egg Retrieval
While it may seem like getting as many eggs as possible during retrieval is ideal, quality trumps quantity. Poor-quality eggs are less likely to fertilise or develop into healthy embryos. Opt for a clinic that emphasises retrieving high-quality eggs rather than maximising numbers.
Your doctor may suggest complementary treatments like CoQ10 supplements or acupuncture to improve egg health. These methods, while not guaranteed, have shown promise in boosting fertility outcomes for some individuals.
6. Use Genetic Testing (When Appropriate)
If you’re over 35 or have a history of miscarriages, ask your doctor about preimplantation genetic testing (PGT). This advanced screening tool identifies chromosomal abnormalities in embryos, increasing the likelihood that a transferred embryo will implant and result in a healthy pregnancy.
7. Care After Embryo Transfer
The two-week wait after embryo transfer can be nerve-wracking, but how you care for yourself during this time is critical.
Take Care Physically
- Maintain light activities—rest if your body feels tired, but try not to remain sedentary for too long.
- Avoid lifting heavy objects or engaging in strenuous activities.
Trust the Process
It’s tempting to analyse every symptom during this phase, but remember that early pregnancy symptoms (or a lack of symptoms) are not definitive indicators. Stay optimistic and lean on your support system to manage any anxiety.
Final Thoughts – What’s Next?
The road to IVF success isn’t about guarantees but about stacking the odds in your favour.
By preparing your body and mind, choosing the right medical team, and making informed decisions, you can empower yourself on this incredible—and often emotional—journey.
If you’re ready to take the next step, reach out to a trusted fertility specialist in pune today.
Schedule a consultation, and start exploring a personalised treatment plan designed just for you.
Don’t wait—your dreams of parenthood could be just one decision away. Contact a fertility specialist now to take that first step.
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About Author
Dr. Supriya Puranik
Gynaecologist & IVF Specialist
MMC -072514 (1993)
Dr. Supriya Puranik, a renowned gynaecologist and infertility expert, leads the IVF & Gynaecology department at Sahyadri Hospitals Momstory in Shivaji Nagar, Pune. She is committed to helping couples overcome infertility challenges.